Evolutionary Ecology

I am really interested in understanding the genetic basis of evolution. How do naturally occurring mutations affect traits, and how does natural selection act on combinations of traits to affect evolutionary change? Using a combination of field and lab studies in the threespine stickleback fish, I hope to identify the genetic basis of multiple traits, and test why certain trait(s) are advantageous.

Greenwood AK, Mills MG, Wark AR, Archambeault SL, Peichel CL (2016) Evolution of schooling behavior in threespine sticklebacks is shaped by the Eda gene. Genetics 203: 677-681.
 
Taylor-Weiner A, Chang T, Gelston L, Wang Y, Mazor T, Esquivel E, Yu A, Seepo S, Olsen S, Rosenberg M, Archambeault S, Abusin G, Brown P, Briones M, Carcamo B, Cooper T, Dahl G, Emanuel P, Fluchel M, Goyal R, Hayashi R, Hitzler J, Hugge C, Liu L, Messinger Y, Monteleone P, Nemecek E, Roehrs P, Schore R, Stine K, Takemoto C, Toretsky J, Costello J, Olshen A, Stewart C, Li Y, Ma J, Gerbing R, Alonzo T, Getz G, Gruber T, Golub T, Stegmaier K, Loh M (2015) The Genomic Landscape of Juvenile Myelomonocytic Leukemia. Nature Genetics 47: 1326-1333.
 
Archambeault S, Ng EF, Rapp L, Cerino D, Bourque B, Solomon-Lane T, Grober MS, Rhyne A, Crow KD (2015) Reproduction, larviculture, and early development of the Bluebanded goby, Lythrypnus dalli, an emerging model organism for studies in evolutionary developmental biology and sexual plasticity. Aquaculture Research 47: 1899-1916.
 
Archambeault S, Crow KD (2014) Molecular divergence between hoxA paralogs is associated with a novel intestinal feature in a percomorph lineage. Master's thesis.
 
Archambeault S, Taylor JA, Crow KD (2014) HoxA and HoxD expression in a variety of vertebrate body plan features reveals an ancient origin for the distal Hox program. EvoDevo 5: 44.
 
LaBrecque JR, Alva-Campbell YR, Archambeault S, Crow KD (2014) Multiple paternity is a shared reproductive strategy in the live-bearing surfperches (Embiotocidae) that may be associated with female fitness. Ecology and Evolution 4: 2316-2329.
 
Kavanaugh DH, Archambeault S, Roopnarine PD, Ledford J (2011) A re-consideration of the taxonomic status of Nebria lacustris Casey (Coleoptera, Carabidae, Nebriini) based on multiple datasets – a single species or a species complex? ZooKeys 147: 199-228.
 
Niemeyer CM, Kang MW, Shin DH, Furlan I, Erlacher M, Bunin NJ, Bunda S, Finklestein JZ, Sakamoto KM, Gorr TA, Mehta P, Schmid I, Kropshofer G, Corbacioglu S, Lang PJ, Klein C, Schlegel P-G, Heinzmann A, Schneider M, Stary J, van den Heuvel-Eibrink MM, Hasle H, Locatelli F, Sakai D, Archambeault S, Chen L, Russell RC, Sybingco SS, Ohh M, Braun BS, Flotho C, Loh ML (2010) Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia. Nature Genetics 42: 794-800.
 
Loh ML, Sakai DS, Flotho C, Kang M, Fliegauf M, Archambeault S, Mullighan CG, Chen L, Bergstraesser E, Bueso-Ramos CE, Emanuel PD, Hasle H, Issa J-P, van den Heuvel-Eibrink MM, Locatelli F, Stary J, Trebo M, Wlodarski M, Zecca M, Shannon KM, Niemeyer CM (2009) Mutations in CBL occur frequently in juvenile myelomonocytic leukemia. Blood 114: 1859-1863.
 
Kotecha N, Flores NJ, Irish JM, Simonds EF, Sakai DS, Archambeault S, Diaz-Flores E, Coram M, Shannon KM, Nolan GP, Loh ML (2008) Single-Cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates. Cancer Cell 14: 335-343.
 
Berman JN, Greer WL, Archambeault S, Loh ML, Riddell C, Morash B, Dumas N, Fernandez CV, Ludman MD (2008) JAK2 V617F positive polycythemia Vera in a child with neurofibromatosis type I. Pediatric Blood & Cancer 51: 689-691.
 
Archambeault S, Flores NJ, Yoshimi A, Kratz CP, Reising M, Fischer A, Noellke P, Locatelli F, Sedlacek P, Flotho C, Zecca M, Emanuel PD, Castleberry RP, Niemeyer CM, Bader P, Loh ML (2008) Development of an allele-specific minimal residual disease assay for patients with juvenile myelomonocytic leukemia. Blood 111: 1124-1127.
2016 – Present
University of Bern, Institute of Ecology and Evolution
PhD Student
Advisor: Catherine Peichel
 
2014 – Present
University of Washington, Molecular and Cellular Biology Graduate Program
PhD Student
Advisor: Catherine Peichel
 
2010 – 2015
San Francisco State University
Master of Science, Biology (Ecology, Evolution and Conservation Biology)
Thesis: “Divergence of hoxa paralogs is associated with a novel percomorph intestinal feature”
Advisor: Karen Crow
 
2008 – 2012
California Academy of Sciences
Molecular Laboratory Assistant
Supervisor: Dave Kavanaugh
 
2005 – 2010
University of California, San Francisco
Staff Research Associate III
Supervisor: Mignon Loh
 
2003 – 2005
University of California, San Francisco
Staff Research Associate II
Supervisor: Kathy Ivenetich
 
1999 – 2003
Connecticut College
Bachelor of Arts, Zoology
Advisor: Philip T. Barnes